White coat hypertension is associated with increased small vessel disease in the brain

Objective: Small vessel disease, as measured by white matter hyperintensity (WMH) in the brain, is known to be associated with increased stroke risk and cognitive impairment. This study explored the relationship between WMH on computerised tomography (CT) and white coat hypertension/effect (WCH/E) in patients with recent transient ischaemic attack (TIA) or lacunar stroke (LS). Design and method: Ninety-six patients recruited for the ASIST trial (Arterial Stiffness in Lacunar Stroke and TIA) underwent measurement of clinic blood pressure (BP) and ambulatory BP monitoring (APBM) within two weeks of TIA or LS. Twenty-three patients had normotension (clinic BP / = 140/90mmHg and day-time ABPM < 135/85mmHg). Arterial stiffness was measured using carotid-femoral pulse wave velocity (PWV) (Complior®, ALAM Medical) and carotid-ankle vascular index (CAVI) (VaSera VS-1500N®, Fukuda Denshi). CT images were scored for WMH using the four-point Fazekas visual rating scale. Patients were grouped into no-mild WMH (scores 0–1) or moderate-severe (scores 2–3) groups. The relationship between BP, vascular stiffness and WMH was explored with t-tests, chi-square and logistic regression accounting for known cardiovascular risk factors. Results: Forty-four percent of patients with WCH/E had moderate-severe WMH compared to 17% of normotensives (p = 0.047). The regression model with WMH as the dependent factor, and WCH/E and cardiovascular risk factors as independent factors showed WCH/E and either CAVI or PWV to be the only independent significant factor contributing to WMH (CAVI:p = 0.038, PWV:p = 0.043)

Solutions of the Generic Non-Compact Weyl Equation

In this paper, solutions of the generic non-compact Weyl equation are obtained. In particular, by identifying a suitable similarity transformation and introducing a non-trivial change of variables we are able to implement azimuthal dependence on the solutions of the diagonal non-compact Weyl equation. We also discuss some open questions related to the construction of infinite BPS monopole configurations.Comment: 12 pages, Latex. Few extra comments and a reference adde

Is pulsar B0656+14 a very nearby RRAT source?

The recently discovered RRAT sources are characterized by very bright radio bursts which, while being periodically related, occur infrequently. We find bursts with the same characteristics for the known pulsar B0656+14. These bursts represent pulses from the bright end of an extended smooth pulse-energy distribution and are shown to be unlike giant pulses, giant micropulses or the pulses of normal pulsars. The extreme peak-fluxes of the brightest of these pulses indicates that PSR B0656+14, were it not so near, could only have been discovered as an RRAT source. Longer observations of the RRATs may reveal that they, like PSR B0656+14, emit weaker emission in addition to the bursts.Comment: 4 pages, 4 figures, accepted by ApJ

Electronic band structure and carrier effective mass in calcium aluminates

First-principles electronic band structure investigations of five compounds of the CaO-Al2O3 family, 3CaO.Al2O3, 12CaO.7Al2O3, CaO.Al2O3, CaO.2Al2O3 and CaO.6Al2O3, as well as CaO and alpha-, theta- and kappa-Al2O3 are performed. We find that the conduction band in the complex oxides is formed from the oxygen antibonding p-states and, although the band gap in Al2O3 is almost twice larger than in CaO, the s-states of both cations. Such a hybrid nature of the conduction band leads to isotropic electron effective masses which are nearly the same for all compounds investigated. This insensitivity of the effective mass to variations in the composition and structure suggests that upon a proper degenerate doping, both amorphous and crystalline phases of the materials will possess mobile extra electrons

Coherently Dedispersed Polarimetry of Millisecond Pulsars

We present a large sample of high-precision, coherently-dedispersed polarization profiles of millisecond pulsars (MSPs) at frequencies between 410 and 1414 MHz. These data include the first polarimetric observations of several of the pulsars, and the first low-frequency polarization profiles for others. Our observations support previous suggestions that the pulse shapes and polarimetry of MSPs are more complex than those of their slower relatives. An immediate conclusion is that polarimetry-based classification schemes proposed for young pulsars are of only limited use when applied to millisecond pulsars.Comment: 28 pages, 10 figures. Text matches version that appeared in ApJS. Full paper with high-resolution figures available at ftp://ftp.jb.man.ac.uk/pub/psr/papers/msppolpton.ps.g

The Quantum Modular Group in (2+1)-Dimensional Gravity

The role of the modular group in the holonomy representation of (2+1)-dimensional quantum gravity is studied. This representation can be viewed as a "Heisenberg picture", and for simple topologies, the transformation to the ADM "Schr{\"o}dinger picture" may be found. For spacetimes with the spatial topology of a torus, this transformation and an explicit operator representation of the mapping class group are constructed. It is shown that the quantum modular group splits the holonomy representation Hilbert space into physically equivalent orthogonal ``fundamental regions'' that are interchanged by modular transformations.Comment: 23 pages, LaTeX, no figures; minor changes and clarifications in response to referee (basic argument and conclusions unaffected

Classical and Quantum Evolutions of the de Sitter and the anti-de Sitter Universes in 2+1 dimensions

Two canonical formulations of the Einstein gravity in 2+1 dimensions, namely, the ADM formalism and the Chern-Simons gravity, are investigated in the case of nonvanishing cosmological constant. General arguments for reducing phase spaces of the two formalisms are given when spatial hypersurface is compact. In particular when the space has the topology of a sphere $S^{2}$ or a torus $T^{2}$, the spacetimes constructed from these two formulations can be identified and the classical equivalence between the ADM and the CSG is shown. Moreover in the $g=1$ case the relations between their phase spaces, and therefore between their quantizations, are given in almost the same form as that in the case when the cosmological constant vanishes. There are, however, some modifications, the most remarkable one of which is that the phase space of the CSG is in 1 to 2 correspondence with the one of the ADM when the cosmological constant is negative.Comment: 37pages Latex (6 figures not included